Size isn't everything

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Size isn't everything

I n his second major book, The Descent of Man and Selection in Relation to Sex, Charles Darwin showed that when animals compete for mates, sexual selection can drive many types of evolutionary change (Darwin, 1871). However, he did not notice that this competition continued even after animals had finished mating. Sperm competition was only described a century later when groundbreaking work show...

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Size isn't everything: lessons in genetic miniaturisation from nucleomorphs.

Nucleomorphs are the vestigial nuclear genomes of eukaryotic algal cells now existing as endosymbionts within a host cell. Molecular investigation of the endosymbiont genomes has allowed important insights into the process of eukaryote/eukaryote cell endosymbiosis and has also disclosed a plethora of interesting genetic phenomena. Although nucleomorph genomes retain classic eukaryotic traits su...

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The evolutionary ecology of testicular function: size isn't everything.

Larger testes are considered the quintessential adaptation to sperm competition. However, the strong focus on testis size in evolutionary research risks ignoring other potentially adaptive features of testicular function, many of which will also be shaped by post-mating sexual selection. Here we advocate a more integrated research programme that simultaneously takes into account the development...

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Pituitary volume and headache: size is not everything.

BACKGROUND Pituitary tumors are commonly associated with disabling headache. The accepted mechanisms for headache are dural stretch and cavernous sinus invasion. OBJECTIVE To determine if there is a relationship between pituitary tumor size and the report of headache. DESIGN We prospectively studied 63 patients who were initially seen with pituitary tumors. Clinical headache scores, pituita...

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The ISNT rule and differentiation of normal from glaucomatous eyes.

OBJECTIVE To determine whether the ISNT rule (that normal eyes show a characteristic configuration for disc rim thickness of inferior > or = superior > or = nasal > or = temporal), widely used for clinical evaluation of the optic nerve head, can differentiate normal from glaucomatous eyes. METHODS All subjects underwent complete eye examination, including achromatic automated perimetry, simul...

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ژورنال

عنوان ژورنال: Nature Reviews Cancer

سال: 2015

ISSN: 1474-175X,1474-1768

DOI: 10.1038/nrc4054